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Acid-Base Disorders - Differential Diagnosis Algorithm Acidemia (pH < 7.35) • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
- Differential Diagnosis ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2 ... #Differential #Diagnosis ... #Algorithm #Causes
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2 ... , pCO2) move in ... #Diagnosis #Nephro
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... (Patm - 47) - (PaCO2 ... Level) [150- (PaCO2 ... #differential #diagnosis
Capnography Measurement of exhaled carbon dioxide can be used to confirm ETT placement, for safer procedural sedation,
- Alveolar CO2 ... • PvCO2 - Mixed ... venous CO2 • ... PaCO2 - Arterial ... waveforms #patterns #diagnosis
ABG vs VBG: Arterial vs Venous Blood Gases ABG PROS: Tells you exactly what the arterial environment looks
vs Venous Blood Gases ... looks like (pH, PaCO2 ... Comparison #pH #pCO2 ... #Diagnosis #Differences
What's in a Blood Gas? VBG vs ABG BOTTOM LINE: VBG is less painful, more easily obtained
very well, and PvCO2 ... #EBM #Diagnosis ... Comparison #PH #PCO2
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
type of hypoxia) PIO2 ... O2 is inspired) PAO2 ... Low SvO2 → Low PaO2 ... #differential #diagnosis ... #causes #pathophysiology
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis pH ↓ pCO2 ↓ -
Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... alkalosis pH ↓ pCO2 ... Interpretation #AcidBase #Diagnosis
Acid Base and Blood Gas Analysis 1. pH - What’s the primary disturbance? 2. pCO2 - What’s the
2. pCO2 - What’s ... the pCO2? ... Medications, Central, ↑ CO2 ... workup #algorithm #diagnosis
Basics of Waveform Capnography Waveform capnography assesses ventilation by monitoring exhaled carbon dioxide Can use measurement and morphology
pathophysiology CLINICAL ... Assessing for CO2 ... Transition as CO2 ... WAVEFORM - Critical ... interpretation #patterns #diagnosis
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