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Voluntary action Emotion, temperature Coughing, sneezing, etc. Physical work Respiratory center in brainstem Coinnervation Medulla Rhythm generator IXth/Xth nerve Respiratory drive: Peripheral Central Mechanosensors in locomotor system Xth nerve Respiration Central chemosensors 个 In CSF: PC02, pH Carotid
Physical work Respiratory ... IXth/Xth nerve Respiratory ... Mechanosensors in lung ... and respiratory ... muscles In blood: #PCO2
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Respiratory or Metabolic ... 7.35-7.45 • PaCO2 ... 35-45 mmHg • PaO2 ... Metabolic: pH pCO2 ... or restrictive lung
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis 1) Start with the Anion Gap (AG). 2)
and ~5 mmHg to pCO2 ... retention • Respiratory ... depression, Obstructive Lung ... Ventilation • Respiratory
Respiratory Oxygenation Cycle - Pathophysiology PO2 and PCO2 By @rev.med #Respiratory #Oxygenation #Cycle #circulation #pathophysiology
Respiratory Oxygenation ... Pathophysiology PO2 ... and PCO2 By @rev.med ... #Respiratory #
Acid-Base Disorders - Differential Diagnosis Algorithm Acidemia (pH < 7.35) • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
HCO3 < 24mmol/L) CO2 ... HCO3 12:10 • Respiratory ... Acidosis (pCO2 ... HCO3 7:10 • Respiratory ... Alkalosis (pCO2
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... Hypoventilation: CNS of Respiratory ... Embolism, Obstructive Lung ... , Interstitial Lung
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2 ... , pCO2) move in ... it is a primary respiratory ... Alkalosis #Metabolic #Respiratory
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis pH ↓ pCO2 ↓ -
- Metabolic + Respiratory ... Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... ↓ - Respiratory ... ↑ - Respiratory
Perform computations online at: ScyMed.com 6th ED ICU-card «ICU, Formulas & Drugs» HEMODYNAMIC PATTERNS Condition SAP CVP PAP PCWP CO C(a-v)02 PVR SVR Hypovolemic shock ↓ ↓ ↓ ↓ ↓ ↑ ↑ ↑ Cardiogenic shock ↓ 1 ↑ 1 1 ↑ Septic shock ↓ ↓ ↓ ↓ ↑ ↓ ↓ ↓ Cardiac Tamponade . ↑ ↑ 1 ↓ → ↑ RV
min 400-600 mL Respiratory ... -PECO2))/PaCO2 ... = >60% Forced Espiratory ... ratio Respiratory ... Tension PACO2
Acid Base and Blood Gas Analysis 1. pH - What’s the primary disturbance? 2. pCO2 - What’s the
2. pCO2 - What’s ... the pCO2? ... Respiratory Acidosis ... production Respiratory ... alkalosis #metabolic #respiratory
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