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management arteritis differential giantcell hematology leukostasis lysis symptoms temporal tls tumor vasculitis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... headaches, vision changes ... them, but urgent rheumatology ... #Temporal #Signs
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
tinnitus, visual changes ... have fever - ACS ... WBC >100k, + lab signs ... acid, Elevated Cr ... #TLS #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Elevated ESR and CRP GCA ... develop in pts with GCA ... and gray matter changes ... #Rheumatology
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