14 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... function test, ANA (e.g ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
AIH-PBC Overlap ... Diagnosis - If suspected ... , AIH diagnosis ... Viral) Management ... #Management #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... normal in mild cases ... hemophilia type (e.g ... Chronic Management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Treat primary cause ... abnormalities - PLT ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
Guidelines for Crises ... CM5 continuous ECG ... consultation with cardiology ... Intraoperative #Checklist ... #Diagnosis #Management
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
other obvious causes ... Transthoracic echocardiogram ... Diagnostic criteria ... - Mechanism: causes ... #management #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Prednisone 5mg/kg ... opacities • Diagnosis ... • Differential Diagnosis ... fluid overload, PCC ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ PLT ... Anemia #oncology #hematology ... #diagnosis #management