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diagnosis hematology hepatology abdominal algorithm alkaline alp biliary chronic cirrhosis elevation gastroenterology leukemia mds monoclonal myelodysplasia myelodysplastic paraproteinemias pbc phosphatase
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Intestine - Other causes ... - Drugs - Pregnancy ... Bone symptoms - Pain ... Primary biliary Cholangitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Examination: • Skin ... bile ducts Differential ... cholestasis of pregnancy ... #cholangitis #diagnosis
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Causes - Differential ... • Skin changes ... dysfunction • PSC ... : • Pregnancy ... #Differential #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Organomegaly+↑RBC/plt ... thrombosis+Pulm HTN+skin ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... compounds, alcohol, lead ... blood count with differential ... #oncology
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