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diagnosis hematology hepatology abdominal algorithm alkaline biliary chronic cirrhosis elevation gap gastroenterology globulin mds myelodysplasia myelodysplastic pbc phosphatase primary protein
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Intestine - Other causes ... - Drugs - Pregnancy ... Bone symptoms - Pain ... Primary biliary Cholangitis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... activity • ↓ LAP ... -> AML: Blast crises ... CLL -> Invade Skin ... #Hematology #Oncology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Examination: • Skin ... obstruction • ALP ... bile ducts Differential ... cholestasis of pregnancy
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Causes - Differential ... • Skin changes ... infarction • Lymphoma/Leukemia ... : • Pregnancy ... #Differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
• Plasma cell leukemia ... gammopathy, and skin ... Castleman disease • AL ... : Lymphoma, Leukemia ... Gap #ProteinGap #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... blood count with differential ... #oncology
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