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diagnosis algorithm hematology elevation workup acidosis acute alkaline alp aplastic cholangitis cirrhosis classification disorders gap globulin hepatitis lactate lactic lfts
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Injury #Differential ... Acute #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Intestine - Other causes ... Cholangitis (PBC ... Infiltrative diseases - PSC ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... intralobular bile ducts causes ... bile ducts Differential ... diagnosis #workup #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... bypass), LFT (liver ... #Workup #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Bile Ducts • PSC ... Duct Stone • Biliary ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... • ↓ WBC • ↓ ... PLT • Reticulocyte ... #oncology #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... or renal injury ... 30mmHg) - Severe anemia ... Injury: • Reduced
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
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