8 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Workup History ... changes), high MCV anemia ... - Bone marrow evaluation ... Refractory ITP, ... #Causes #Workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Evaluation for ... products or D-dimer ... impairment #TTP ... #Workup #Hematology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... dysfunction, and/or disorders ... total body stores Evaluation ... : • History - Diet ... consider other diagnosis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... other neurological disorders ... antibody that works ... limb or joint disorders
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... Thalassemia, Sickle cell anemia ... #differential #diagnosis
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
500 mL in a 70 kg ... phlebotomy/ blood work ... during clinical evaluations ... of unnecessary diagnostic ... #differential #diagnosis
Palpitations - Differential Diagnosis Framework

What?
• It is an unpleasant awareness or sensation that the heart is
- Differential Diagnosis ... Have the patient tap ... Hyperthyroidism • Anemia ... Psychiatric: • Panic disorder ... palpitations: PVC
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
red bone marrow, e.g ... Biopsy: Solitary disorder ... • No CRAB - no anemia ... Evaluation? ... #Workup #Hematology