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diagnosis hematology management differential aplastic cell elevation gap globulin hodgkins lactate lactic lymphoma mds myelodysplasia myelodysplastic plasmacytoma protein proteingap rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
www.ncbi.nlm.nih.gov/pmc ... perfusion - shock->treatments ... before beginning treatment ... 30mmHg) - Severe anemia ... classification
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... ) Classification ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... Sarcoidosis) • Liver ... Thalassemia, Sickle cell anemia ... • Other causes ... Comment on type
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
TYPE IV RTA, TYPE ... vasculitis: 10%-16% Liver ... renal tubular acidosis ... Adenocarcinoma Treatment ... lubricants • Pharmacologic
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
common - GI tract, liver ... • No CRAB - no anemia ... UPEP, Serum IFE, FLC ... Bone marrow Treatment ... #Plasmacytoma #Oncology
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