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diagnosis differential hematology algorithm alkaline hepatitis phosphatase acidosis aflp aih autoimmune disorders fatty gap globulin hodgkins hyophosphatasia injury lactate lactic
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... biliary Cholangitis (PBC ... Diagnosis #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... , PSC, IgG4, HLH ... Bilirubin - +/- elevation ... Enzyme Elevation ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... Intrahepatic Cholestasis Management ... Pregnancy #hepatology ... obgyn #diagnosis #management
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... hepatocellular pattern of liver ... Anti-LKM & Anti-ALC ... (rare) - IgG Elevation ... #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
: INR/PT, aPTT(liver ... changes), high MCV anemia ... bypass), LFT (liver ... not required in all ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... • Pernicious anemia ... • Elevation of ... phosphate &/or • Elevation ... Hyophosphatasia #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... www.ncbi.nlm.nih.gov/pmc ... Elevation Type ... 30mmHg) - Severe anemia ... #typea #typeb #classification
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... ) Classification ... #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... Castleman disease • AL ... Sarcoidosis) • Liver ... Thalassemia, Sickle cell anemia ... • Other causes
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