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diagnosis differential hematology alkaline aplastic disorders gap globulin hepatitis injury management phosphatase platelet protein proteingap thrombocytopenia workup
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Bilirubin - +/- elevation ... Enzyme Elevation ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
: INR/PT, aPTT(liver ... anemia (vegan, ... bypass), LFT (liver ... not required in all ... #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Significant ↓ PLT ... - infiltrates (anemia ... count • ↓Hg & PLT ... #Hematology #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - EBV - CMV ... virus (EBV) • Leukemia ... • ↓ WBC • ↓ PLT ... #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
• Plasma cell leukemia ... Castleman disease • AL ... Sarcoidosis) • Liver ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia
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