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diagnosis hematology mds myelodysplastic syndrome treatment aflp apml causes classification differentiation fatty hematololgy hodgkins liver lymphoma monoclonal myelodysplasia obgyn obstetrics
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... @ZhuoerXie #Aplastic ... #Anemia #diagnosis ... #oncology #hematololgy
Causes of Aplastic Anemia #Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Anemia #Aplastic ... #Pathophysiology ... Pathology #Treatment #Management ... #Differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... • ↓ WBC • ↓ PLT ... #Anemia #oncology ... #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... #treatment #hematology ... #oncology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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