8 results
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Phytonadione), 4-factor PCC ... Andexxa), 4-factor PCC ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... cholangitis #diagnosis #workup ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... for decreased PLT ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... heparin-PF4 complex → plt ... hypercoagulable state and plt ... , Bivalirudin, DOAC ... Management #Treatment #Hematology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... www.ncbi.nlm.nih.gov/pmc ... www.ncbi.nlm.nih.gov/pmc ... phlebotomy/ blood work ... Hospitalization #causes #pathophysiology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... , PSC, Viral hepatitis ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... differential #diagnosis #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
• No CRAB - no anemia ... UPEP, Serum IFE, FLC ... Oncology #Diagnosis #Workup ... #Hematology