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diagnosis differential hematology causes diabetes endocrinology alkaline biliary cholangitis cirrhosis disorders dm2 gap globulin glp1 hospitalization hyophosphatasia leukemia low oncology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
GLP-1 Agonists ... -1 Agonists are ... They work primarily ... #GLP1 #Agonists ... #Pharmacology #Dosing
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Nucleotidase • ALT ... obstruction • ALP ... cholangitis #diagnosis #workup ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... Diagnosis #Causes #Workup ... #hematology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
) - First Oral GLP ... -1 Agonist Dosing ... oral route by using ... Otherwise, it works ... semaglutide #Diabetes #Pharmacology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... cases diagnosed during ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... Significant ↓ PLT ... - infiltrates (anemia ... count • ↓Hg & PLT ... #Leukemia #Hematology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
- Pathophysiology ... adversely affecting all ... phlebotomy/ blood work ... lying down (Fox et al ... Hospitalization #causes #pathophysiology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Castleman disease • AL ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... differential #diagnosis #hematology
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