11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... for decreased PLT ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... intralobular bile ducts causes ... obstruction • ALP ... cholangitis #diagnosis #workup ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... = nonspecific (nausea ... , ↑Tbili/Dbili/AP ... Cr, ↓Glucose, ↓PLT ... Liver #Pregnancy #hepatology
Intern Pocket Cards - Inpatient Bowel Regimen Guide
Osmotic agents (draws water into bowel, thereby loosening stool
Polyethylene glycol - Nausea ... water enema - Discomfort ... during procedure ... #constipation #pharmacology ... #table #agents
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
during childhood ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Causes of Monoclonal ... Castleman disease • AL ... Thalassemia, Sickle cell anemia ... • Other causes
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... activity • ↓ LAP ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... phlebotomy/ blood work ... prolonged rest can cause ... lying down and can cause ... #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Action, ↑ EFR & AP ... Action, ↓ EFR & AP ... Action, ←→ EFR & AP ... phase 2 (↑ERP & ↑AP ... #pathophysiology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
) - First Oral GLP ... -1 Agonist Dosing ... Otherwise, it works ... drug to remain stable ... semaglutide #Diabetes #Pharmacology