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diagnosis hematology biliary differential oncology pbc primary betablockers causes cholangitis gap globulin hospitalization indications leukemia management plasmacytoma protein proteingap pseudoanemia
Beta-Blockers in Cirrhosis • Pathophysiology • Indications: Prevention of decompensation, Prevention of first variceal bleeding,
Beta-Blockers in Cirrhosis ... • Pathophysiology ... gastropathy • Dosing ... #hepatology #management ... #pharmacology #
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary Cirrhosis ... Coordinated T & B cell ... cascade with T-cell ... Primary #Biliary #Cirrhosis ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... cholestasis → Cirrhosis ... #diagnosis #workup ... #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... Significant ↓ PLT ... - infiltrates (anemia ... count • ↓Hg & PLT ... #Leukemia #Hematology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
- Pathophysiology ... first two days during ... phlebotomy/ blood work ... our reasoning during ... Hospitalization #causes #pathophysiology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... myeloma • Plasma cell ... Liver disease: Cirrhosis ... Thalassemia, Sickle cell ... anemia • Other
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • No CRAB - no anemia ... UPEP, Serum IFE, FLC ... Oncology #Diagnosis #Workup ... #Hematology
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