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diagnosis hematology oncology management acute alkaline apl aplastic apml auer coagulation dic differential disorders disseminated hyophosphatasia intravascular low mds mentzerindex
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... (blood). ... features in most cases ... #Hematology #Clinical ... #Smear
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... -> AML: Blast crises ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... involve one, two, or all ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... smear • Bone marrow
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... deficiency • blood ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... proportion of the red blood ... a decrease in all ... well as varying clinical ... These causes could
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... virus (EBV) • Leukemia ... • ↓ WBC • ↓ PLT ... result from low blood
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... ABO incompatible blood ... organ damage Clinical ... • Peripheral smear ... Treat primary cause
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