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diagnosis hematology management oncology classification algorithm treatment workup abscess acidosis agglutinin alkaline alp aplastic approach bloodsmear borrelia coagulation cold dic
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm Blood ... Normochromic RBCs on Smear ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... plateletcount), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Algorithm Normal Blood ... Smear • Drugs ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Peripheral Smear ... count with differential ... smear • Bone marrow ... Syndromes #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... -> AML: Blast crises ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... of Peripheral blood ... smear - Shows schistocytes ... immune hemolytic anemia ... WBC count and differential
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
on Peripheral Blood ... Smear 23M Somali ... 12.5, WBC 14, Plt ... The table below ... microscopy #pathology #clinical
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... result from low blood ... #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood ... #hematology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... • Peripheral smear ... Treat primary cause ... Coagulation #diagnosis #causes
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