9 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... anemia Sickled ... #hematology #microscopy ... interpretation #clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... @mjcascio #MAHA ... #anemia #Hematology ... #Pathology #Smear
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA ... Hemoglobin Defects: Sickle ... cell anemia, Thalassemias ... - Peripheral Blood ... Smear ↑ abnormal
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
smear showed numerous ... , a form of hemolytic ... inflexible and prone to hemolysis ... #NEJM #clinical ... #smear
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood ... #anemia #hematology
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
smears the small ... autosplenectomy in sickle ... can be found in hemolytic ... #Clinical #Path ... #BloodSmear #Blood
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... • Peripheral smear ... TTP/DITMA) - MAHA ... Schistocytes - MAHA
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form ... #Leukemia #Hematology
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Smear 23M Somali ... 12.5, WBC 14, Plt ... The table below ... be treated in a single ... microscopy #pathology #clinical