5 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... peripheral blood smear ... changes), high MCV anemia ... dysplasia on the smear ... #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... -> AML: Blast crises ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... • Peripheral smear ... • Neutropenia, anemia ... Leukemia #diagnosis #workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... Marrow Failure • Chronic ... Workup: • Complete ... Peripheral blood smear
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Adult form: Less ... thigh bones -> chronic ... • Pernicious anemia ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology