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hematology oncology differential gammopathy protein 4factorpcc agglutinin cell cold comparison disease flc gammopathies gap globulin hemolytic ife laboratory leukemia management
Monoclonal Gammopathy Testing Strengths, Weaknesses and Accuracy Compared - SPEP - IFE - FLC
Monoclonal Gammopathy ... UPEP / IFE #Monoclonal ... Testing #Protein #Diagnosis ... #MGRS #MGUS #SPEP ... Laboratory #Comparison #Table
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... insufficiency, Anemia ... : • Abnormal FLC ... #Significance #hematology ... #diagnosis #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Organomegaly+↑RBC/plt ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma and Monoclonal ... 40 ml/min A - Anemia ... if this is is monoclonal ... #Gammopathies #MGUS ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... significance (MGUS ... disease #hemolytic #anemia ... #hematology #diagnosis
REBEL Review 90: Weight Based 4 Factor PCC Dosing #Hematology #Management #Table #4FactorPCC #REBELReview #Pharmacology #Dosing
Based 4 Factor PCC ... Dosing #Hematology ... #Management #Table ... #REBELReview #Pharmacology ... #Dosing #WeightBased
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... Gammopathy Include: • MGUS ... Thalassemia, Sickle cell anemia ... #differential #diagnosis ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... - infiltrates (anemia ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... tissue composed of monoclonal ... • No CRAB - no anemia ... UPEP, Serum IFE, FLC ... #Workup #Hematology
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