12 results
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Monoclonal Gammopathy ... UPEP / IFE #Monoclonal ... Gammopathy #Testing #Protein ... #Diagnosis #MGRS ... Laboratory #Comparison #Table
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
protein level < ... No evidence of anemia ... insufficiency, Anemia ... #Significance #hematology ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... 40 ml/min A - Anemia ... gamma gap (total protein ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
REBEL Review 90: Weight Based 4 Factor PCC Dosing 

#Hematology #Management #Table #4FactorPCC #REBELReview #Pharmacology #Dosing
Based 4 Factor PCC ... Dosing #Hematology ... #Management #Table ... #REBELReview #Pharmacology ... #Dosing #WeightBased
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Protein/M Component ... Organomegaly+↑RBC/plt ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
- Differential Diagnosis ... Nephrotic syndrome • Protein-losing ... • Asbestos • Uremia ... Effusion #Pulmonary #Diagnosis ... #Algorithm #Hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
it represents a monoclonal ... Causes of Monoclonal ... Thalassemia, Sickle cell anemia ... #differential #diagnosis ... #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... autoimmune hemolytic anemia ... conditions Diagnosis ... syndrome • Burns • Protein-losing ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... - infiltrates (anemia ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
12.5, WBC 14, Plt ... The table below ... outer membrane proteins ... LBRF can be diagnosed ... can be used for diagnosis