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diagnosis hematology oncology cll leukemia lymphocytic cell cold differential disease gap globulin hemeonc hemolytic management plasmacytoma protein proteingap solitary
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... lymphoproliferative disorder ... • Symptoms of anemia ... • hemolytic anemia ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... 5) Symptoms of anemia ... cytopenias (ITP, AIHA ... fludarabine) 3) Monoclonal
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... lymphoproliferative disorders ... • Neutropenia, anemia ... thrombocytopenia • AIHA ... Leukemia #diagnosis #workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... it represents a monoclonal ... Causes of Monoclonal ... Connective tissue disorders ... Thalassemia, Sickle cell anemia
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Biopsy: Solitary disorder ... tissue composed of monoclonal ... • No CRAB - no anemia ... Oncology #Diagnosis #Workup ... #Hematology
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