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diagnosis hematology oncology cll lymphocytic cell differential erythematosus gap globulin hemeonc lupus management mds myelodysplasia myelodysplastic plasmacytoma protein proteingap rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... in adults • Disorder ... 5) Symptoms of anemia ... cytopenias (ITP, AIHA ... fludarabine) 3) Monoclonal
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... lymphoproliferative disorders ... • Neutropenia, anemia ... #CLL #Chronic ... #diagnosis #workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... - infiltrates (anemia ... /Cytopenias • AIHA ... #Hematology #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... • Plasma cell leukemia ... Connective tissue disorders ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Marrow Failure • Chronic ... Myelogenous Leukemia ... Workup: • Complete
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) • Endocrine disorders ... Hematologic: • AIHA ... • Anemia of inflammation ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Biopsy: Solitary disorder ... tissue composed of monoclonal ... • No CRAB - no anemia ... Oncology #Diagnosis #Workup ... #Hematology
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