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diagnosis hematology oncology chronic cll differential gap globulin hemeonc management protein proteingap
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... cytopenias (ITP, AIHA ... AIHA, PRCA) • Treatment ... fludarabine) 3) Monoclonal ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... thrombocytopenia • AIHA ... Hypogammaglobulinemia • Warm AIHA ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... count • ↓Hg & PLT ... Leukemia): • Lymphocytes ... /Cytopenias • AIHA ... #Hematology #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... • Plasma cell leukemia ... Cirrhosis, ETOH, autoimmune ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia
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