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diagnosis hematology differential oncology globulin paraproteinemias proteingap
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gap (Total Protein ... Albumin > 4) Work-up ... • Plasma cell leukemia ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Protein/M Component ... Organomegaly+↑RBC/plt ... Coagulopathy) SMZL: • AIHA ... (-) hemolytic anemia ... Pseudohyponatremia • ↓anion gap
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... - infiltrates (anemia ... count • ↓Hg & PLT ... /Cytopenias • AIHA ... #Hematology #Oncology
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