9 results
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Hematologic disorder ... No evidence of anemia ... insufficiency, Anemia ... , or a related disorder ... #Significance #hematology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Spot PC (protein ... chains - Screen for monoclonal ... for detection of monoclonal ... C4 - Test for disorders ... #testing #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... for decreased PLT ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Spot PC (protein ... C4 - Test for disorders ... chains - Screen for monoclonal ... for detection of monoclonal ... #workup #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
in adults • Disorder ... 5) Symptoms of anemia ... marrow failure with anemia ... fludarabine) 3) Monoclonal ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... lymphoproliferative disorders ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... • Plasma cell leukemia ... Connective tissue disorders ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Workup: • Complete
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Biopsy: Solitary disorder ... tissue composed of monoclonal ... • No CRAB - no anemia ... Oncology #Diagnosis #Workup ... #Hematology