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diagnosis causes algorithm aflp obstetrics pregnancy saag albumin biliary cholangitis disease gap globulin gradient hbv hellp hematology hepatitisb hepatomegaly hepbv
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... develops (DIC, ascites ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... #hepatology #obstetrics
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... - Nonalcoholic fatty ... liver disease ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
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 Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... or chronic hepatitis ... Diagnosis #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Non-Malignant • Fatty ... Liver • Cysts ... Primary Biliary Cirrhosis ... Algorithm #Causes #Hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... /acute hepatitis ... metastasis • Fatty ... Diagnosis #causes #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
>1.1 g/dl): - Cirrhosis ... - Alcoholic hepatitis ... - Massive liver ... disease - Acute fatty ... #Diagnosis #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
- Cirrhosis ... - Alcoholic hepatitis ... - Acute fatty ... Causes #diagnosis #differential ... #hepatology #SAAG
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
/Liver failure ... or higher • Liver ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... : < 1 • Cirrhosis ... #injury #hepatitis ... #differential # ... diagnosis #algorithm #hepatology
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