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ana antibody antinuclear cytoplasmic differentiation management monoclonal nuclear paraproteinemias patterns rheumatology syndrome testing
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... initiation • Differential ... fluid overload, PCC ... coagulopathy, RRT/IMV as ... #hematology #oncology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - PBC ... : - PBC, SSc ... , PBC/SSc OS, PBC ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt ... WAIHA • CAD • PCH ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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