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bony differential hematology hemophagocytic hlh lesions lymphohistiocytosis management msk oncology perioperative plasmacytoma preop preoperative rheumatology risk solitary stratification summary treatment
Diagram of different types of bone tumors that can occur around the knee on XRay -
on XRay - Age > ... Healed NOF • Giant cell ... Diagnosis #Bony ... #Differential #Radiology ... #adult
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Biological + Bone ... Cytopenia +++ (Plt ... /ml, ↑ LDH • Bone ... diseases: SLE+++, Adult-onset ... inhibitors under evaluation
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... obstruction X-Ray ... Diagnosis? ... Evaluation? ... UPEP, Serum IFE, FLC
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Preoperative Risk Evaluation ... Change in clinical ... risk Chest X-ray ... events or death (CARP ... stratification #diagnosis
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