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differential algorithm primary aflp alkaline autoimmune biliary cirrhosis elevation fatty gap globulin hematology injury lfts liverenzymes obgyn obstetrics pathophysiology pbc
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... obstruction • ALP ... : • Viral hepatitis ... #cholangitis #diagnosis ... #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... Primary biliary Cholangitis ... (PBC) - Other ... Infiltrative diseases - PSC ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Drugs • AIH ... Bile Ducts • PSC ... • Alcoholic hepatitis ... #Algorithm #Causes
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
been reported (eg AIH-PBC ... , AIH diagnosis ... Anti-LKM & Anti-ALC ... #AIH #Diagnosis ... #Management #Hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
(PSC) PSC is a ... asymptomatic at diagnosis ... disease management ... #diagnosis #management ... #summary #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... : Viral Hepatitis ... Pregnancy #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Castleman disease • AL ... Sarcoidosis) • Liver ... , PBC, PSC, Viral ... #differential #diagnosis ... #hematology
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