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hematology differential biliary cholangitis cirrhosis common disorders gap globulin hypogammaglobulinemia immunodeficiency immunology pbc platelet primary protein proteingap thrombocytopenia variable
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... : • Viral hepatitis ... #workup #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... IgA, IgG, IgM (CVID ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... , PBC, PSC, Viral ... Thalassemia, Sickle cell anemia ... #differential #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... diseases and hepatitis ... autoimmune hemolytic anemia ... DDX - Other causes ... #diagnosis #management
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