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diagnosis hepatology algorithm abnormal cholangitis elevated gap globulin hepatitis injury lfts liver liverfunctiontests pbc primary protein proteingap rheumatology scleroderma sclerosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... bile ducts Differential ... fungal, viral infections ... #Cirrhosis #PBC ... cholangitis #diagnosis #workup
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Ducts - PBC ... , PSC, Alcoholic ... Hep, Drugs, Infection ... stricture, PSC,
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury: • Infectious ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
pericarditis • Hepatic: PBC ... (primary biliary ... calcinosis • Pulmonary ... signs #symptoms #testing ... #workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Include: • Viral infections ... Liver disease: Cirrhosis ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis
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