8 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Parenchyma • Infectious ... hepatitis, Acute biliary ... Malignancy, 1° PBC ... , 1° PSC, Cystic
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
or higher • Liver ... bile ducts Differential ... fungal, viral infections ... cholangitis #diagnosis #workup ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Ducts - PBC ... , PSC, Alcoholic ... stricture, PSC,
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Injury: • Infectious ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... smear, HIV/HCV testing ... : INR/PT, aPTT(liver ... #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
pericarditis • Hepatic: PBC ... (primary biliary ... calcinosis • Pulmonary ... signs #symptoms #testing ... #workup
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
haemophilum • Tropical setting ... Hematologic malignancy ... (elevations of liver ... • Dyspnea, • Chest ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Include: • Viral infections ... Sarcoidosis) • Liver ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis