10 results
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
to multi-focal biliary ... asymptomatic at diagnosis ... with persistently active ... colorectal and hepato-biliary ... #Cholangitis #diagnosis
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Diagnosis: Latent ... staining, NAA (PCR ... Treatment: Active ... #TB #Diagnosis ... #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Diagnosis: Latent ... staining, NAA (PCR ... Treatment: Active ... #TB #Diagnosis ... #Management #Treatment
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
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reported (eg AIH-PBC ... Diagnosis - If suspected ... , AIH diagnosis ... regarding need for treatment ... azathioprine (check TPMT activity
Incidental Finding of Oleothorax - A chest radiograph showed a dense opacity in the upper area
The differential diagnosis ... her history of treatment ... for tuberculosis ... oleothorax — a treatment ... #Clinical #PCC #
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... other agents are: activity ... purposes including PCP ... choice, both for treatment ... #Pharmacology #Antibiotics
Macrolides - Erythromycin, Clarithromycin, Azithromycin - Antibiotics Class Overview

50S Ribosomal Inhibitor (PO and IV)
Spectrum: Atypical organisms
Azithromycin - Antibiotics ... Legionella), also some activity ... Strep throat in PCN ... Used for MAC treatment ... #Pharmacology #Antibiotics
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... hepatitis, primary biliary ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... muscarinic agonists • Active
Anti-Pseudomonal - Antibiotics Class Overview

Pseudomonas aeruginosa is a non-fermenting Gram-negative bacillus that inhabits a variety of
Anti-Pseudomonal - Antibiotics ... Ertapenem has no activity ... so use only if PCN-allergic ... empiric Pseudomonas treatment ... Polymyxin B(IV) #Pharmacology
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Mycobacterium Tuberculosis ... no evidence of active ... and molecular diagnostic ... Mycobacterium #Tuberculosis ... infections #HIVAIDS #pharmacology