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diagnosis algorithm differential primary lfts management psc causes comparison elevated gap globulin hematology hepatitis injury liver liverenzymes liverfunctiontests pathophysiology protein
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Disease: Primary Biliary ... Cirrhosis vs Primary ... Sclerosing Cholangitis ... pathophysiology #pbc ... #psc #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... • Fatigue PBC ... #Cirrhosis #PBC
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... stricture, PSC,
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
(PSC) PSC is a ... • COVERT - PSC ... patients with PSC ... pathogenesis of PSC ... • CANCER - PSC
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... hepatitis: < 1 • Cirrhosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
disease US — Normal ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... 1.5x ULN and/or abnormal ... survey disease #PBC ... #Treatment #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Liver disease: Cirrhosis ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... chain assay • An abnormal
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