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Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
of Sickle Cell Crises ... Clinical Manifestations ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... #Differential #Diagnosis ... #Causes #Workup ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... Diagnosis: • ... Differential Diagnosis ... #cholangitis #diagnosis ... #workup #hepatology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
and workup ... 1) Clinical diagnosis ... Alzheimer - 1st cause ... Dementia - 2nd cause ... #Diagnosis #Geriatrics
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... remain subject to clinical ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... , AIH diagnosis ... Hepatitis (eg Viral) Management ... #Management #Hepatology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
help and inform clinical ... tube ❹ Rapid diagnosis ... • Diagnostic ... Plan definitive management ... #Management #Workup
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... Maternal Support - Critical ... Liver #Pregnancy #hepatology
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
hypovolaemia or combined causes ... adult, 10 ml.kg-1 paediatric ... o Endocrine cause ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
and Management ... heparin-PF4 complex → plt ... : • Clinical Suspicion ... non-heparin A/C if clinical ... #Hematology #HemeOnc