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diagnosis differential dermatology cryoglobulins dermatologic disease gpa granulomatosis hematology lupus management monoclonal oncology paraproteinemias polyangiitis rash signs size skin sle
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Primary: 50% Cutaneous ... Urticarial/LCV) - Cryoglobulinemic ... : • Cutaneous ... : • Behcet Disease ... #dermatology #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... systemic lupus erythematosus ... syndrome - Behcet ... dermatomyositis #Size #Classification ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Henoch-Schönlein purpura) • Cutaneous ... systemic lupus erythematosus ... diagnosis #types #classification ... #rheumatology # ... vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Behçet Syndrome ... aphthous ulcers, cutaneous ... strong sign of cutaneous ... differential #diagnosis #rheumatology ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... : • Acute cutaneous ... Non-autoimmune rheumatologic ... lymphopenia, low PLT ... #Diagnosis #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
purpura (16%) • Painful ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... purpura • Mixed cryoglobulinemia ... rash #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... aphthous ulcerations (painful ... ) • Cutaneous Lesions ... azathioprine #Behcet ... signs #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Strong sign of cutaneous ... ischemia • Skin: Erythematous ... / ANCA + MPO) Cryoglobulinemic ... • Behcet syndrome ... Differential #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... Immunotactoid GN & Cryoglobulinemic ... Organomegaly+↑RBC/plt ... Autoimmunity: • -MM/WM: Vasculitis ... (Cryoglobulinemic
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