16 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thromboembolism (7%) • CNS ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... Rhinosinusitis, CNS ... this morphology Treatment ... #Management #treatment ... #fungal #infectiousdiseases
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... permeability Diagnosis ... Erythematosus #SLE #CNS ... #neurology #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV-Associated CNS ... Antimicrobial treatment ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... bacteria: Viral, Fungal ... Immunocompromise Treatment ... Tissue penetration (CNS ... • Secondary to Treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
> 4 days → add fungal ... G6PD first) DIC ... Treat underlying cause ... ) - Symptoms: CNS ... ) - Symptoms: CNS
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... leukostasis syndrome: CNS ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
: • Direct fungal ... especially the CNS ... MC: CNS CSF: • ... ) #Mycoses #InfectiousDiseases ... #Fungal #Diagnosis
Waterborne Infections - Differential Diagnosis Framework

Infections that can be acquired from fresh water, brackish water, sea
- Differential Diagnosis ... dermatitidis CNS ... - And, in rare cases ... #Differential #Diagnosis ... #InfectiousDiseases
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Adenocarcinoma Treatment