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diagnosis differential eosinophilia clinical dermatology drugreaction management skinrash anemia common cvid extravascular hemolysis hemolytic hypogammaglobulinemia immunodeficiency immunology intravascular myopathy myositis
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... #Eosinophilia #Legs ... #Photo #UCSDH
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... Eosinophilia #Photo ... #UCSDH
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... Eosinophilia #Trunk #Photo ... #UCSDH
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Parasites Drugs: - DRESS ... (vasculitis / autoimmune ... Hypereosinophilic Syndrome ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... hemoglobinuria (PNH ... differential #diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
unless levels are less ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... be any age) Autoimmune ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
arthralgia, arm/leg ... tract, and often causes ... purpura (lower legs ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
TAFRO TAFRO syndrome ... hypergammaglobulinemia, and less ... mesothelioma, etc - Autoimmune ... histopathologic changes in LNs ... diagnosis #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... RP-ILD), dermato-rheumatologic ... aspiration > 50% of pts ... statins - probably caused ... Myositis #Myopathy #rheumatology
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