14 results
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... Eosinophilia #Photo ... #UCSDH
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... Eosinophilia #Legs #Photo ... #UCSDH
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Syndrome): Formerly ... medication (in this case ... Images #Clinical #Dermatology ... Eosinophilia #Trunk #Photo ... #UCSDH
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... (RA, Sjogren's) ... antiphospholipid syndrome ... #differential #hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Parasites Drugs: - DRESS ... (vasculitis / autoimmune ... Hypereosinophilic Syndrome ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiencies - PNH ... Associated - SLE, Sjogren's ... Differential #Diagnosis #hematology ... #rheumatology #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... be any age) Autoimmune ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... #Syndrome #Rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... hemoglobinuria (PNH ... differential #diagnosis #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... infection • Autoimmune ... Often Secondary to Autoimmune ... classification #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren ... disease • Non-autoimmune ... rheumatologic diseases ... • May involve PNS ... Erythematosus #Diagnosis #Rheumatology