8 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... uremic syndrome ... hemoglobinuria (PNH ... #differential # ... diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... deficiencies - PNH ... #Diagnosis #hematology ... #nonpalpable #dermatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... disease (younger pts ... ) Differential ... #anemia #hematology
Lemierre's Syndrome on Neck POCUS with IJ Thrombosis - Transverse View

Male with high fever and right
Differential/diagnosis ... case. ... septic emboli in lungs ... #Jugular #Thrombosis ... #Clinical #Ultrasound
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... and autoimmune hemolytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Lemierre's Syndrome on Neck POCUS with IJ Thrombosis - Sagittal View

Male with high fever and right
Differential/diagnosis ... case. ... septic emboli in lungs ... #Jugular #Thrombosis ... #Clinical #Ultrasound
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... (Type I) renal tubular ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... classification #hematology