8 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... disease • Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... #Management #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... Clinical Features ... • May involve PNS ... Chronic B-cell activation
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rheumatic pain Clinical ... Diagnosis: • A clinical ... Rule out other causes ... diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... Diagnosis #Management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
JVD, Orthopnea/PND ... acute coronary syndrome ... the determined cause ... #differential #algorithm ... #management #cardiology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid Syndrome ... - 1 or more clinical ... maternal chromosomal causes ... excluded Testing: • Lupus ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... caused by uncontrolled ... activation of the ... Clinical Presentation ... #Hematology #HemeOnc