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diagnosis rheumatology actinomycosis antinxp2 antinxp2dm cell common cvid dermatomyositis disseminated histiocytosis hypogammaglobulinemia immunodeficiency immunology langerhans lch nejm sjogrens sulfur syndrome
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... Chest CT: • Ground-glass ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
revealed multiple pulmonary ... Biopsy of the lung ... bacterial infection caused ... #NEJM #clinical ... #radiology #CT #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... #Diagnosis #Management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... auricular papules Clinical ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... dermatology
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
populations) CLINICAL ... • Pulmonary Symptoms ... CNS involvement: ... Imaging: X-rays, CT ... Histiocytosis #Diagnosis #Management
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