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rheumatology management dermatology differential druginduced activation algorithm alkaline antimda5 antimda5dm autoimmune comparison dermatomyositis dil hepatology hyophosphatasia low macrophage mas myopathy
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... Autoimmune Vasculitis (lupus ... Fecal occult blood test ... #dermatology #physicalexam
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Most cases diagnosed ... membrane into the CNS ... Waddling gait - Difficulty ... Phosphatase: • Other causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... Petechial or purpuric rash ... SJIA], systemic lupus ... Liver function tests ... Activation #Syndrome #Diagnosis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... -74%] • Blood tests ... #dermatology #diagnosis
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
lupus cases, drug-dependent ... to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... #diagnosis #treatment
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... Symptoms: • Gottron rash ... Polymyositis or ALS ... aspiration > 50% of pts ... statins - probably caused
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