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differential clinical algorithm extravascular intravascular rash rheumatology skin alkaline alp anemia canimorsus capnocytophaga cutaneous hemolytic hepatology hyophosphatasia low monoclonal mucormycosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... • PCH • PNH ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... hemoglobinuria (PNH ... Extravascular #Causes ... #hematology #anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... DIC/TTP/HUS - Hemolytic ... deficiencies - PNH ... #hematology #rheumatology ... #nonpalpable #dermatology
Rickettsialpox Eschar 40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis? Rickettsialpox R akari classic
Diagnosis? ... Pts can recover ... rickettsia) Dx: serology ... rakari #clinical #photo ... #skinrash #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... blood test • Serology ... #Algorithm #Causes ... #dermatology #physicalexam
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... immunosuppressed pts ... cutaneous mucor cases ... #dermatology #skin ... #clinical #photo
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Amyloidosis (CVS+PNS ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... membrane into the CNS ... respiratory failure • Neurologic ... Waddling gait - Difficulty ... Phosphatase: • Other causes
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... the key to the diagnosis ... the organism is difficult ... Canimorsus #Skin #Rash #dermatology ... #clinical #photo
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... #Rheumatology
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