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diagnosis dermatology algorithm rheumatology management oncology classification hemolytic clinical pathophysiology photo purpura skinrash extravascular hemeonc hemolysis hypopigmentation infectiousdiseases lesions neurology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Hemolysis - Differential ... circulation - Infections ... immune-complex hemolytic anemia ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Myelofibrosis Infectious ... • Rheumatic disorders ... Iron deficiency anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... - Hemolytic anemia ... deficiencies - PNH ... #Diagnosis #hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
erythrocytes from the intravascular ... integrity (trauma, infection ... vasculitis) or disorders ... #Rash #Petechiae ... Palpable #Algorithm #Differential
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... drug induced • Infections ... IVIG infusion Intravascular ... classification #hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... • Factitious disorder ... • Sickle Cell Anemia ... Cryoglobulinemia Infectious ... Diagnosis #Algorithm #causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... procedures - Infection ... changes), high MCV anemia ... #Differential # ... #Workup #hematology
Skin Hypopigmentation - Differential Diagnosis Algorithm Diffuse Congenital - Generalized hypopigmentation of hair, eyes, skin • Phenylketonuria
- Differential ... sclerosis (white "ash ... Hypopigmentation #disorders ... #skin #dermatology ... Diagnosis #Algorithm #causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
, autoimmune disorder ... • Symptoms of anemia ... ) Differential ... the RBCs causing intravascular ... #hematology #diagnosis
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