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diagnosis anemia hemolytic differential algorithm atlas basics classification cold dermatology disease extravascular hemolysis hodgkins key lesions lymphoma management mds myelodysplasia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... hemoglobinuria (PNH ... . primary cold agglutin ... lymphoproliferative disorders ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... disease (younger pts ... the RBCs causing intravascular ... hemolytic #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
platelet decrease - PNH ... Agglutination - Cold agglutinins ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... • Autoimmune disorders ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... lesions that contain pus ... a generalized disorder ... area of dermal oedema ... #Diagnosis #Dermatology
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