17 results
diagnosis differential obstetrics pregnancy comparison intravascular liver anemia extravascular hemolysis hemolytic hepatitis management obgyn table ttphus workup alkaline alp arterial
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Thrombocytopenia ... of Pregnancy (AFLP ... schistocytes, DIC ... child * Severe cases ... #hematology #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Non-lmmune: • HELLP ... • TTP/HUS • DIC ... #Causes #Hematology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Thrombocytopenia ... schistocytes, DIC ... child * Severe cases ... #AFLP #Obstetrics ... #OBGyn #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Microangiopathy: DIC ... - Pregnancy: HELLP ... Medicine @SCVMCMed #Thrombocytopenia ... Diagnosis #Framework #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... rapidly develops (DIC ... Preeclampsia, HELLP ... Liver #Pregnancy #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
, no necrosis HELLP ... features: Hemolysis, Thrombocytopenia ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Differential Diagnosis Algorithm ... • Pregnancy - AFLP ... , HELLP Moderate ... Others #LFTs #Hepatology ... #Causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... : - Thrombocytopenia ... marrow disease - DIC ... deficiencies - PNH ... Differential #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation (DIC ... ) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... differential #diagnosis #hematology
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