8 results
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... , caused by the ... differentiating between the diagnosis ... #PhysicalExam # ... Video #Clinical
Abnormalities in Rate and Rhythm of Breathing 
Normal 
The respiratory rate is about 14—20 per min
has a number of causes ... the midbrain or pons ... hyperventilation syndrome—a ... Abnormalities #Abnormal ... #Diagnosis #PhysicalExam
Quincke's Pulse in a patient with a normal echocardiogram (non-valvular)

A 70 y/o man presents with new
dyspnea, orthopnea/PND ... is identified (video ... EtOH causes thiamine ... AorticRegurgitation #Diagnosis ... #PhysicalExam #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12%), Raynaud ... Diagnosis #Management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cooled from the normal ... Arthralgias • Raynaud ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... fluid (CSF) is abnormal ... tract, and often causes ... #Rheumatology
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
cold exposure if Raynaud's ... seen in Reiter's syndrome ... Nail #Diseases #Abnormal ... #Pathology #Diagnosis ... Clinical #Signs #PhysicalExam
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... joint pain and Raynaud ... aspiration > 50% of pts ... • Myositis • Raynaud ... statins - probably caused